João Siffert, M.D., is the president and chief executive officer of Design Therapeutics and is a member of our board of directors. Dr. Siffert brings more than 30 years of experience to Design Therapeutics, having successfully led organizations responsible for multiple drug development programs in biotech and pharma from pre-clinical to regulatory approvals and commercial launches in the U.S. and Europe. He joined Design Therapeutics from Abeona Therapeutics where he was the chief executive officer and a member of the board of directors. Prior to Abeona, Dr. Siffert held a number of medical and scientific roles, including as chief scientific and medical officer, and has served at biopharmaceutical companies including Nestle Health Science, Avanir Pharmaceuticals, Ceregene Inc., Avera Pharmaceuticals and Pfizer. Dr. Siffert also served as an independent director for Avexis, Inc. and Alcobra Pharma (now Arcturus Therapeutics). Before joining industry, Dr. Siffert spent seven years in academic practice as a neuro-oncologist at Beth Israel Hospital and as an assistant professor of neurology at Albert Einstein College of Medicine in New York City. Dr. Siffert earned his M.D. from the University of São Paulo, Brazil, and his MBA from Columbia University. He completed medical residencies in pediatrics at New York University (NYU) School of Medicine and in neurology at Harvard Medical School, followed by a fellowship training in neuro-oncology at NYU. The American Board of Neurology and Psychiatry certified Dr. Siffert in 1996.